Figure 1.

Linkage Disequilibrium among KIR genes. (A) Two LD maps of the KIR region were constructed using Arlequin v3.5, comparing D’ and r² values between pairwise combinations of the 16 KIR genes. Each block on the maps represent either the D’ (left map) or r² (right map) value calculated. The two color keys indicate the range of values represented by different colors. Gene names are shown at the left and bottom of each map. (B) A cartoon representation of the KIR region, showing the combinations or blocks of KIR genes into commonly seen motifs. The color-coded key at the bottom indicates the motif or region that each gene is linked to, with the 2DL5-2DS35 block hatched to highlight both centromeric and telomeric residence.