Figure 4. Comparison the HNF4α homodimer and the PPARγ-RXRα heterodimer complexes on DR1 DNA.
a, The PPARγ-RXRα heterodimer on DR1, b, The HNF4α homodimer on DR1, and c) their overlap when the DR1 sequences are superimposed, showing the distinct domain-domain arrangements in these two complexes. The two complexes are shown in an identical fashion with respect to the DNA sequence facing the viewer.