Figure 1.

Mutiscale approach to modeling tissue production by cells encapsulated in hydrogels. Refer to the next sections for the parameters. Left: chondrocytes encapsulated within a PEG hydrogel, shown at day 3 after encapsulation. Cytosol of live cells fluoresce green showing the chondrocytic round morphology. Nuclei of dead cells fluoresce red. Scale bar indicates 100 microns. Right: chondroitin sulfate elaboration (red) by chondrocytes encapsulated within a degradable PEG hydrogel after 28 days in vitro. Cell nuclei are stained blue. Scale bar indicates 50 microns.