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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Cell Signal. 2012 Oct 17;25(1):359–371. doi: 10.1016/j.cellsig.2012.10.009

Fig. 5. High glucose induces ICAM-1 and VCAM-1 expressions via IKK, p65, JNK, and c-Jun.

Fig. 5

A, HG induces ICAM-1 expression via IKK, p65, JNK, and c-Jun. HAEC infected with lentiviral particles expressing IKKβ, IKKγ, p65, JNK, or c-Jun shRNA (MOI 0.5 for 48 h) were treated with HG for 12 h and then analyzed for ICAM-1 (A) or VCAM-1 (B) mRNA (12 h) expression by RT-qPCR. Knockdown of respective proteins was confirmed by immunoblotting, and are shown in C. A, B, *P < at least 0.01 vs. NG, †P < at least 0.001 (n=12).