TABLE 3.
Adverse neonatal outcomes by fetal lung maturity test
| Neonatal outcome | Lung maturity | |||
|---|---|---|---|---|
| Determined by TDx-FLM II assay and phosphatidylglycerol only: lamellar body count removed (n = 114) | Determined by TDx-FLM II assay only (n = 93) | Determined by phosphatidylglycerol only (n = 58) | Determined by lamellar body count only (n = 113) | |
| Gestational age at positive fetal lung maturity results, wka | 36.6 ± 1.2 | 36.6 ± 1.2 | 36.9 ± 1.1 | 36.6 ± 1.2 |
| Composite adverse neonatal outcome, n (%)b | 20 (17.5) P < .01c |
18 (19.4) P < .01c |
10 (17.2) P < .01c |
19 (16.8) P < .01c |
| Delivery room interventions: oxygen or more, n (%) | 25 (21.9) P = .08 |
20 (21.5) P = .05 |
13 (22.4) P = .22 |
31 (27.4) P < .01c |
| Hypoglycemia, n (%) | 23 (21.1) P < .01c |
21 (22.6) P < .01c |
10 (17.2) P < .01c |
19 (16.8) P < .01c |
| Intravenous fluids for hypoglycemia, n (%) | 3 (2.6) P = .03c |
3 (3.2) P = .02c |
1 (1.7) P = .18 |
3 (2.7) P = .03c |
| Gavage feeds, n (%) | 5 (4.4) P < .01c |
4 (4.3) P < .01c |
2 (3.5) P = .03c |
7 (6.2) P < .01c |
| Phototherapy, n (%) | 8 (7.0) P < .01c |
7 (7.5) P < .01c |
3 (5.2) P = .08 |
8 (7.1) P < .01c |
| Sepsis evaluation, n (%) | 11 (9.7) P = .01c |
10 (10.8) P < .01c |
7 (12.1) P = .01c |
14 (12.4) P < .01c |
| Treatment with antibiotics, n (%) | 3 (2.6) P = .15 |
3 (3.2) P = .12 |
2 (3.5) P = .15 |
3 (2.7) P = .16 |
| Central venous line, n (%) | 1 (0.9) P = .30 |
1 (1.1) P = .26 |
1 (1.7) P = .18 |
1 (0.9) P = .30 |
| Neonatal intensive care admission, n (%) | 14 (12.3) P < .01c |
13 (14.0) P < .01c |
7 (12.1) P < .01c |
13 (11.5) P < .01c |
| Oxygen supplementation, n (%) | 3 (2.6) P = .08 |
3 (3.2) P = .06 |
2 (3.5) P = .09 |
3 (2.7) P = .08 |
Comparison is between study group (34 0/7 weeks’ gestation born after positive fetal lung maturity, as determined by different fetal lung maturity tests, and the reference group (39 0/7 to 40 6/7 weeks’ gestation).
a
Data are given as mean ± SD;
b
Consists of neonatal intensive care admission, phototherapy, antibiotic treatment, intravenous fluids for hypoglycemia, or gavage feeding;
c
Denotes significant differences: P < .05.
Kamath. Neonatal outcomes after documented fetal lung maturity. Am J Obstet Gynecol 2011.