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The NO/ADMA/DDAH Pathway and the pharmacological Inhibition of DDAH1 leading to higher ADMA levels and subsequent regulation of NO production. DMA = dimethylamine. ADMA = asymmetric Dimethylarginine. SDMA = symmetric Dimethylarginine. L-NMMA = monomethyl arginine. PRMTs = Protein Arginine Methyltransferases. NO = Nitric Oxide. NCE = New Chemical Entity
