Table 1.

Ex vivo susceptibility of 34 Plasmodium falciparum isolates from Dakar to chloroquine (CQ), monodesethylamodiaquine (MDAQ), lumefantrine (LMF), dihydroartemisinin (DHA), quinine (QN), mefloquine (MQ) and doxycycline (DOX)

Drug	No	Isolate IC50				Resistance or reduced susceptibility
		Mean	CI95%	Min	Max	Cut-off	%
CQ	34	41.3 nM	26.7-64.0	5.1	1958	77 nM	24.2
MDAQ	34	19.4 nM	13.3-28.4	1.6	179	61 nM	11.8
LMF	34	9.8 nM	6.3-15.2	0.77	139	115 nM	2.9
DHA	32	3.6 nM	2.8-4.6	1.2	11.0	12 nM	0
QN	34	141.3 nM	93.7-213.0	5.2	1195	611 nM	9.7
MQ	32	30.1 nM	22.2-41.0	5.3	86.9	30 nM	62.1
DOX	32	9.2 μM	6.5-12.9	0.5	41.9	37 μM	10.3

Mean: geometric mean.

CI95%: 95% confidence interval.