Table 7.
Multivariate Cox regression analysis of various factors for prognosis of lung cancer patients
| Progression-free survival | |||
|
| |||
| Variables | Hazard ratio (95% CI) | Unfavorable / Favorable | P |
|
| |||
| FER overexpression | 2.335 (1.043-5.232) | Positive / Negative | 0.033* |
| Age (years) | 2.250 (1.082-4.681) | ≥65 / < 65 | 0.030* |
| Sex | 1.311 (0.840-2.046) | Male / Female | 0.332 |
| Smoking habit | 1.346 (0.464-3.904) | Ever / Never | 0.585 |
| Histological type | 1.142 (0.356-3.664) | Adeno / Squamous | 0.823 |
| Disease stage | 2.570 (0.963-6.859) | IIA-IIIA / IA, IB | 0.059 |
| T factor | 3.258 (1.533-6.922) | T2 / T1 | 0.002* |
| N factor | 1.745 (0.587-5.183) | N1, N2 / N0 | 0.316 |
| Adjuvant chemotherapy | 1.343 (0.757-2.381) | No / Yes | 0.323 |
| EGFR mutation | 1.493 (0.635-3.512) | Negative / Positive | 0.358 |
|
| |||
| Overall survival | |||
|
| |||
| Variables | Hazard ratio (95% CI) | Unfavorable / Favorable | P |
|
| |||
| FER overexpression | 2.220 (1.064-4.631) | Positive / Negative | 0.039* |
| Age (years) | 2.266 (1.104-4.652) | >65 / < 65 | 0.026* |
| Sex | 1.392 (0.699-2.775) | Male / Female | 0.264 |
| Smoking habit | 1.509 (0.531-4.286) | Ever / Never | 0.440 |
| Histological type | 1.350 (0.422-4.316) | Adeno / Squamous | 0.613 |
| Disease stage | 4.267 (1.474-12.353) | IIA-IIIA / IA, IB | 0.007* |
| T factor | 2.618 (1.221-5.615) | T2 / T1 | 0.013* |
| N factor | 3.743 (1.191-11.768) | N1, N2 / N0 | 0.024* |
| Adjuvant chemotherapy | 1.183 (0.445-3.139) | No / Yes | 0.741 |
| EGFR mutation | 1.329 (0.554-3.189) | Negative / Positive | 0.524 |
CI, confidence interval.
*
P < 0.05.