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HF led to increase of biomarkers associated with metabolic impairments. Feeding with HF or CF for 14 weeks, body weight (A) was measured every week; fast glucose (B) was detected every two weeks, fast insulin (C), IPGTT (D) and IPTT (E) were detected before mating. AUC of IPGTT and IPTT changed (F). Error bars depicted the standard error of the mean. *P<0.05, **P<0.01 or ***P<0.001 compared to the CF control.
