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Distribution of NYHA class after 6 months in ESA (red bars) and placebo (blue bars) (upper left panel); six minute hall walk distance in ESA (red circles and placebo (blue triangles) (upper right panel); peak VO2 in ESA (red circles) and placebo (blue triangles) (lower left panel) and quality of life measures for KCCQ (solid lines) and MLWFQ (dashed lines) (lower right panel) at baseline and after 3 and 6 months of therapy.
