Table 2.

Adjusted probabilities of mortality, survival and primary causes of death among patients, who received allogeneic hematopoietic cell transplantation with myeloablative conditioning for malignant disease according to spleen status.

	Normal Spleen	Splenomegaly	Splenic irradiation	Splenectomy	p-value
100-day adjusted mortality (95% confidence interval)	22% (21–23)	23% (21–25)	23% (19–28)	24% (21–28)	n.s.
3-year adjusted survival (95% confidence interval)	50% (49–52)	50% (47–52)	51% (45–56)	50% (45–54)	n.s.
Primary causes of death					<0.001
Infection	1050 (24%)	158 (20%)	33 (18%)	56 (17%)
Bacterial	277 (26%)	37 (23%)	8 (24%)	15 (27%)
Fungal	360 (34%)	49 (31%)	10 (30%)	22 (39%)
Viral	172 (16%)	24 (15%)	3 (9%)	10 (18%)
NOS/Other	241 (23%)	48 (30%)	11 (33%)	9 (16%)
Organ Failure	967 (22%)	159 (24%)	39 (29%)	65 (22%)
Pulmonary Failure	553 (58%)	86 (54%)	22 (56%)	34 (52%)
Liver	139 (14%)	31 (19%)	5 (13%)	9 (14%)
Other	275 (28%)	42 (26%)	12 (31%)	22 (34%)
GVHD	789 (19%)	141(19%)	30 (17%)	49 (16%)
Primary disease	549 (13%)	161 (21%)	30 (17%)	62 (20%)
Hemorrhage/Vascular	238 (6%)	41 (5%)	10 (6%)	22 (7%)
Graft Failure	110 (3%)	17 (2%)	5 (3%)	9 (3%)
Second Malignancy	63 (1%)	7 (<1%)	4 (<1%)	12 (<1%)
Other	154 (4%)	20 (3%)	6 (3%)	11 (4%)
Unknown	115 (3%)	20 (3%)	7 (4%)	6 (2%)

Abreviation: n.s., p value > 0.05.