Table 3.
Demographic details of the complete baseline Alzheimer’s Disease Neuroimaging Initiative-1 dataset used to compute hippocampal volumes. Twenty-four month follow-up data are also reported. MCI = Mild Cognitive Impairment, MCI converters (cMCI) are ADNI1 participants that converted from a diagnosis of MCI to AD through a 24-month study window, while MCI reverters (rMCI) are participants that reverted from a clinical evaluation of MCI to being normal elders. MCI stable or sMCI are subjects that had a diagnosis of MCI that did not change over a 24-month period. MMSE=Mini Mental State Exam, LM1 – Logical Memory Test 1 Immediate Recall, AVLT = Auditory Verbal Learning Test (Sum of trials I–IV), ICV = intracranial volume.
| NC | MCI Total | MCI Converters | MCI Reverters | MCI Stable | AD | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N (baseline) | 227 | 412 | 134 | 13 | 262 | 200 | ||||||
| N (24 month follow-up) | 173 | 254 | 95 | 10 | 148 | 111 | ||||||
| Average Age (SD) (Years) | 76.0 | (5.0) | 74.7 | (7.4) | 74.4 | (7.2) | 73.5 | (9.0) | 75.0 | (7.5) | 75.6 | (7.7) |
| Average Education (SD) (years) | 16.1 | (2.8) | 15.7 | (3.0) | 15.7 | (2.9) | 15.8 | (2.5) | 15.7 | (3.1) | 14.7 | (3.2) |
| Gender (M) | 118 | 262 | 81 | 9 | 172 | 103 | ||||||
| Average MMSE Score (SD) (/30) | 29.12 | (1.00) | 27.07 | (1.89) | 26.65 | (1.73) | 27.54 | (1.39) | 27.17 | (1.81) | 23.28 | (2.04) |
| Average Scan Interval (SD) (months) | 24.7 | (1.3) | 24.6 | (1.1) | 24.6 | (1.1) | 24.4 | (1.8) | 24.6 | (1.0) | 24.7 | (1.6) |
| Average ICV SD) (ml) | 1329.8 | (132.3) | 1346.3 | (137.0) | 1327.2 | (147.0) | 1398.1 | (164.1) | 1353.4 | (129.4) | 1311.9 | (146.6) |