Table 1.
Sequence of endogenous neuropeptide FF and RF-related peptides.
| Peptide | Species | Sequence |
|---|---|---|
| Precursor: pro-NPFFA | ||
|
| ||
| NPFF | Human | SQAFLFQPQRF |
| Bovine | SPAFLFQPQRF | |
| Mouse | SPAFLFQPQRF | |
| Rat | NPAFLFQPQRF | |
|
| ||
| NPAF (NPSF for the last 8 residues† | Human | AGEGLNSQFWSLAAPQRF |
| Bovine | AGEGLSSPFWSLAAPQRF | |
| Mouse | QFWSLAAPQRF | |
| Rat | EFWSLAAPQRF | |
|
| ||
| Precursor: pro-NPFFB | ||
|
| ||
| RFRP-1 | Human | MPHSFANLPLRF |
| Bovine | MPPSAANLPLRF | |
| Mouse | VPHSAANLPLRF | |
| Rat | VPHSAANLPLRF | |
|
| ||
| RFRP-3 (NPVF) | Human | VPNLPQRF |
| Bovine | AMAHLPLRLGKNRED | |
| SLSRWVPNLPQRF | ||
| Mouse | VNMEAGTRSHFPSLPQRF | |
| Rat | ANMEAGTMSHFPSLPQRF | |
†
Note that ‘NPSF’ has been used in the literature to describe both an eight amino acid short version of NPAF and a 37 amino acid extended version of rat RFRP-1.
NPFF: Neuropeptide FF; RFRP: RF-related peptide.
Reproduced with permission from [6].