Table 1: List of selected products included in this study

ATC code	Therapeutic Area	INN	Product	Strength	Pharmaceutical form	Company	EMA Authorisation [18]
A02BC04	Proton pump inhibitors	Rabeprazole	Pariet	10 mg	Tabs	Janssen-Cilag	November 1998
A08AA10	Obesity	Sibutramine	Reductil	10 mg	Caps	Abbott	April 2001
A08AB01	Obesity	Orlistat	Xenical	120 mg	Tabs	Roche	July 1998
A10BG02	Diabetes	Rosiglitazone maleate	Avandia	4 mg	Tabs	GSK	July 2000
A10BG03	Diabetes	Pioglitazone hydrochloride	Actos	30 mg	Tabs	Eli Lilly	October 2000
B01AB05	Acute coronary syndrome	Enoxaparin	Lovenox	100 mg	Prefilled syringe	Sanofi-Aventis	November 2000
B01AX05	Other antithrombotic agents	Fondaparinux	Arixtra	2.5 mg/0.5 ml	Prefilled syringe	GSK	March 2002
J05AE07	Protease inhibitors	Fosamprenavir calcium	Telzir	700 mg	f/c tabs	GSK	July 2004
J05AE10	Protease inhibitors	Darunavir	Prezista	300 mg	Tabs	Janssen-Cilag	February 2007
J05AF06	HIV	Abacavir sulfate	Ziagen	300 mg	Tabs	GSK	July 1999
J05AF07	HIV	Tenofovir disoproxil fumarate	Viread	245 mg	Tabs	Gilead	February 2002
J05AG03	Non-nucleoside reverse transcriptase inhibitors	Efavirenz	Stocrin	600 mg	f/c tab	MSD	May 1999
J05AX09	Other antiviral	Maraviroc	Celsentri	150 mg	Tabs	Pfizer	September 2007
L01BC06	Oncology	Capecitabine	Xeloda	500 mg	Tabs	Roche	February 2001

ATC = Anatomical Therapeutic Chemical, INN = International Non-Proprietary Name f/c=film coated