Table 2.

Comparison of self-reported and Medication Event Monitoring System adherence by month of clinic attendance.

Month	N	7-day self-report (%)	7-day MEMS (%)	Difference between 7-day self-report and 7-day MEMS (%)	P value of difference between 7-day self-report and 7-day MEMS	30-day MEMS (%)	Difference between 7-day self-report and 30-day MEMS (%)	P value of difference between 7-day self-report and 30-day MEMS	Proportion with 7-day MEMS adherence >90%
1	532	98.6	88.9	9.7	<0.01	89.7	8.9	<0.01	0.76
2	527	98.9	87.1	11.8	<0.01	87.2	11.7	<0.01	0.73
3	490	98.8	84.8	14.0	<0.01	85.9	12.9	<0.01	0.69
4	452	98.7	83.6	15.1	<0.01	84.3	14.4	<0.01	0.66
5	410	98.9	85.7	13.2	<0.01	85.5	13.4	<0.01	0.69
6	386	98.2	84.8	13.4	<0.01	83.8	14.4	<0.01	0.68
Meana		98.7	86.0	12.7	<0.01	86.2	12.5	<0.01	0.71

Linear trend in difference between 7-day self-report and 7-day Medication Event Monitoring System (MEMS) over 6 months was statistically significant (P<0.01).

^aAverage across patient-months (N=2797).