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. 2013 Feb 4;110(12):4804–4809. doi: 10.1073/pnas.1216100110

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Fig. 2. — LAC treatment corrects abnormalities in BDNF and glutamate release in FSL rats. (A) BDNF levels in prefrontal cortex and hippocampus of FRL and FSL rats treated with saline or LAC for 21 d. n = 6. P < 0.05 vs. all other values (*) or vs. FRL rats treated with LAC (#). F = 25.4 and 13.6 for hippocampus and prefrontal cortex, respectively. (B) Levels of acetylated H3K27 bound to BDNF promoter gene in prefrontal cortex and hippocampus of FRL and FSL rats treated with saline or LAC for 21 d, n = 4. P < 0.05 vs. all other values (*) or vs. FSL rats treated with saline (#). F = 31.78 and 8.099 for hippocampus and prefrontal cortex, respectively. (C) Serum BDNF levels in FRL and FSL rats treated with saline or LAC for 21 d. n = 6. *P < 0.05 vs. FSL rats treated with saline. F = 8.9. (D) LAC effect on depolarization-evoked glutamate and GABA release in superfused hippocampal synaptosomes, n = 6. *P < 0.05 vs. all other values.