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Biometal alterations in childhood disorders.
| Childhood disorder | Associated gene(s) | Biometal concentrations |
|---|---|---|
| Wilson's disease | ATP7B | Copper ↑ |
| Menkes disease | ATP7A | Copper ↓ |
| Neuronal ceroid lipofuscinoses | At least 10 genes | Zinc, manganese, copper, iron, cobalt, sodium ↑ |
| Potassium, magnesium ↓ | ||
| Neurodegenerative disorders with iron accumulation | At least 7 genes | Iron ↑ |
