Table 3.
Baseline echocardiograms for adult male mice
| Echocardiogram Measurements | Control (N=14) | Sertraline (N=17) |
|---|---|---|
| Shortening Fraction (%) | 37 ± 2.1 | 35 ± 1.6 |
| Ejection Fraction (%) | 66 ± 2.7 | 64 ± 2.1 |
| Interventricular septum, diastole (mm) | 0.8 ± 0.05 | 0.9 ± 0.04 |
| LV Posterior wall, diastole (mm) | 1.0 ± 0.1 | 1.0 ± 0 |
| LV Posterior wall, systole (mm) | 1.5 ± 0.1 | 1.5 ± 0.1 |
| LV Mass (mg) | 147 ± 7.5 | 139 ± 6.7 |
| LV Internal Diameter, diastole (mm) | 4.0 ± 0.1 | 3.7 ± 0.1* |
| LV Internal Diameter, systole (mm) | 2.6 ± 0.1 | 2.4 ± 0.1 |
| LV Volume, diastole (μL) | 71 ± 4.3 | 59 ± 4.2 |
| LV Volume, systole (μL) | 25 ± 2.7 | 22 ± 2.4 |
| Stroke Volume (μL) | 46 ± 2.6 | 37 ± 2.3* |
p < 0.05.