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. 2013 Mar 8;110(10):167–173. doi: 10.3238/arztebl.2013.0167

Table 1. Indication criteria for liver transplantation in patients with acute liver failure of various causes*.

Criteria Indications
King’s College criteria Prothrombin time >100 sec (= Quick <7% or inr >6.7)
or at least three of the following:
  • Unfavorable etiology (cryptogenic hepatitis, halothane hepatitis, drug toxicity)

  • Icterus more than 7 days before encephalopathy

  • Age <10 years or >40 years

  • Prothrombin time >50 sec (= Quick <15% or inr >4)

  • Serum bilirubin >300 µmoL/L (>17.5 mg/dL)

Special criteria for paracetamol toxicity Arterial pH <7.3
or all three of the following:
  • Prothrombin time >100 sec (= Quick <7% or inr >6.7)

  • Creatinine >300 mmoL/L (>4 mg/dL)

  • Encephalopathy grade 3 or 4

Clichy criteria (in recipients with viral hepatitis) Encephalopathy grade 3 or 4
and
  • Factor V <20% in recipients <30 years

or
  • Factor V <30% in recipients >30 years

*Modified from (e31)