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. 2013 Feb 19;94(2):133–143. doi: 10.1111/iep.12010

Figure 1.

Figure 1

Liver sections of control and symptomatic dog naturally infected with Leishmania (L.) chagasi: (a,b). Control dog: (a) Lower magnification showing portal tract and collagen fibers in black color. Ammoniacal silver-staining (Bars = 62 μm); (b) higher magnification showing a delicate reticulin fibers detected by ammoniacal silver-staining. Ammoniacal silver-staining (Bars = 16 μm). Infected dog. “Rogers′ Cirrhosis (c–f). (c) Lower magnification showing portal tract in the left and collagen fibers in black color in the hepatic lobule. Ammoniacal silver-staining (Bars = 62 μm); (d) higher magnifications showing a conspicuous collagen thickening in the space of Disse and hepatic cells had become isolated from the sinusoidal blood by the fibropoiesis (black arrows). Observe dense and coiled fibers extend through sinusoids (white arrows). Ammoniacal silver-staining (Bars = 16 μm). (e) Beyond an intense fibrilopoesis, note a presence of one intralobular granuloma at the right corner of the picture. Ammoniacal silver-staining (Bars = 32 μm). (f) Detail of figure (e) showing granuloma with rare reticulin fibers inside. Ammoniacal silver-staining (Bars = 16 μm). PV, portal vein; S, sinusoids vessels; HA, hepatic artery.