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. 2012 Dec 28;3(2):43–53. doi: 10.1002/brb3.113

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Effects of injection of neural progenitor cells (NPCs) on angiogenesis in the ischemic brain. The experimental protocol in this study is depicted (A). Animals were sacrificed on day 7 or 28 after microsphere embolism-induced cerebral ischemia (ME). Representative images of double staining for bromodeoxyuridine (BrdU; green) and vascular endothelial marker (RECA; red) in the peri-infarct regions of sham-operated (sham; B–D, H–J), ME (E–G) or vehicle-injected ME (Vehicle-ME K–M), and NPC-injected ME (NPC-ME; N–P) rats on days 7 and 28 after ME are shown. White arrows indicate colocalization of BrdU with RECA. Scale bars represent 50 μm.