Table 2. Biochemical assay results for Ndja and Moz.
| Enzyme |
Females and males
(n=20+20) |
Females only
(n=20) |
Males only
(n=20) |
|||
|---|---|---|---|---|---|---|
| Ndja | Moz | Ndja | Moz | Ndja | Moz | |
| P450 | ||||||
| Mean | 1.45 × 10−3 | 0.72 × 10−3 | 1.8 × 10−3 | 0.7 × 10−3 | 1.1 × 10−3 | 0.75 × 10−3 |
| Fold change | 1.93 | 2.57 | 1.46 | |||
| P | 0.0051 | 0.0030 | 0.029 | |||
| GST | ||||||
| Mean | 0.26 | 0.10 | 0.34 | 0.11 | 0.18 | 0.095 |
| Fold change | 2.6 | 3.09 | 1.89 | |||
| P | 0.015 | 0.0066 | 0.20 | |||
| pNPA | ||||||
| Mean | 0.12 | 0.092 | 0.14 | 0.075 | 0.11 | 0.11 |
| Fold change | 1.3 | 1.86 | 1 | |||
| P | 0.064 | 0.0038 | 0.88 | |||
| α-Napthyl acetate | ||||||
| Mean | 1.6 × 10−3 | 0.99 × 10−3 | 1.6 × 10−3 | 0.59 × 10−3 | 1.6 × 10−3 | 1.4 × 10−3 |
| Fold change | 1.61 | 2.71 | 1.14 | |||
| P | 0.010 | 0.0011 | 0.53 | |||
| β-Napthyl acetate | ||||||
| Mean | 1.6 × 10−3 | 1.2 × 10−3 | 1.6 × 10−3 | 1.0 × 10−3 | 1.7 × 10−3 | 1.4 × 10−3 |
| Fold change | 1.33 | 1.6 | 1.21 | |||
| P | 0.083 | 0.11 | 0.38 | |||
| Inhibition of AChE by propoxur/% | ||||||
| Mean | 92.8 | 92.6 | 96.5 | 96.9 | 89.2 | 88.2 |
| P | 0.83 | 0.75 | 0.58 | |||
Abbreviations: AChE, average percentage of inhibition of AChE by propoxur; GST, glutathione S-transferase activity; P450, equivalent units of cytochrome P450; pNPA, esterase activity with p-nitrophenyl acetate; α-/β-napthyl acetate, micromoles of α-/β-napthol produced per minute per milligram of protein.
P-values in bold show significant difference (<0.05) between Ndja and Moz.