Genetic Deletion of HOS1, HOS2, or HOS3 Has No Effect on erg3-Mediated Azole Resistance, Related to Figure 3
To determine if other KDACs contribute to fluconazole (FL) resistance, we tested the impact of the deletion of HOS1, HOS2 or HOS3 individually and in combination with HDA1 in an erg3 mutant background in a FL MIC assay. Cultures were grown in YPD at 30° for 48 hr and growth was measured as in Figure 1.