Figure 1.

Satb1 Is Specifically Expressed by MGE-Derived Cortical Interneurons

(A) Double immunostaining of brain sections from GAD67^GFP heterozygous mice for SATB1 (A1) and GFP (A2). (A) shows a merge of images in A1 and A2. Arrows indicate GFP⁺SATB1⁺ and arrowheads indicate GFP⁺SATB1⁺ neurons. Insets in (A)–(A2) show GFP⁺SATB1⁺ cells.

(B–E) Double immunostaining of cortical sections from GAD67^GFP animals for SATB1 (B1, C1, D1, and E1) and LHX6 (B2), SST (C2), PV (D2), and VIP (E2). Images in (B)–(E) are merges of (B1) and (B2), (C1) and (C2), (D1) and (D2), and (E1) and (E2), respectively.

(F) Quantification of the percentage of LHX6⁺, SST⁺, PV⁺, NPY⁺, CR⁺, and VIP⁺ interneurons coexpressing SATB1 (n = 3 animals per each interneuron marker analysis).