Figure 3.

Overexpression of SATB1 in MGE Precursors Induces a Gene Expression Profile Associated with Mature Cortical Interneurons

(A) Schematic presentation of the experimental strategy.

(B) Quantification (fold change) of transcripts in two independent experiments for the indicated genes following electroporation of control (pRFP; white bars) and Satb1-expressing (pSATB1-RFP; red bars) vectors.

(C and D) Triple immunostaining of a cortical section from GAD67^GFP E18.5 embryo for GFP (green), KCC2 (red), and SATB1 (blue). (D) Magnification of the box in (C). (C1)–(C3) and (D1)–(D3) show the single colors of (C) and (D), respectively. Note that all GFP⁺SATB1⁺ interneurons coexpress KCC2.

See also Figures S1 and S3.