Table 3.

Expression of HGF and Met between primary tumors and corresponding Metastases (21 pairs with Primary, LN and liver; 30 pairs of primary tumor and liver, 42 pairs of PT and LN).

	T	RN	L	cases	T	L	cases	T	RN	cases
HGF expression between primary tumors and corresponding metastases
	N	N	N	3	N	N	7	N	N	11
	N	P	N	3	N	P	2	N	P	7
	P	P	N	1	P	N	3	P	N	0
	P	P	P	14	P	P	18	P	P	24
Concordance: 17cases				17/21	25 cases		25/30	35 cases		35/42
Rate: (both N and P)				81%			83%			83%
Discordance: 4 cases				4/21	5 cases		5/30	7cases		7/42
Rate (discordance)				19%			17%			17%
Friedman Test				total	McNemar		total	McNemar		total
P=0.039				21 cases	P=1.000		30cases	P=0.016		42 cases
Met expression (N and P) between primary tumors and matched metastases
	N	N	N	0	N	N	1	N	N	1
	P	P	P	16	N	P	2	N	P	4
	P	P	N	2	P	N	4	P	N	1
	N	P	P	1	P	P	23	P	P	36
	N	N	P	1
	P	N	P	1
Concordance: 16 cases				16/21	24 cases		24/30	37 cases		37/42
Rate: (both N and P)				76%			80%			88%
Discordance: 5 cases				5/21	6 cases		6/30	5 cases		5/42
Rate (discordance)				24%			20%			12%
Friedman Test				21 cases	McNemar		30cases	McNemar		42 cases
P=1.000					P=1.000			P=0.375

T: Primary tumor; RN: Regional lymph node metastasis; L: Synchronous liver metastasis; N: negative, P: positive.