Table 5.
HGF | Mean copy numbers | 95% CI | Statistical method and P value | |
---|---|---|---|---|
HGF expression at the RNA level in one subgroup of TxN0M1 and TxN0M0 | ||||
TxN0M1 | 9 | 138 relative copies |
78-216 | independent t test p= 0.589 |
TxN0M0 | 9 | 125 relative copies |
67-209 | |
HGF expression at the RNA level in the other subgroup of TxN1-2M1, TxN1-2M0 and TxN0M0 | ||||
TxN1-2M1 | 21 | 245 relative copies |
134-337 | One way ANOVA p=0.007 TxN1-2M1vs TxN1-2M0 p=0.036 TxN1-2M1vs TxN0M0 p=0.008 TxN1-2M0vsTxN0M0 p=0.574 |
TxN1-2M0 | 21 | 163 relative copies |
90-266 | |
TxN0M0 | 21 | 158 relative copies |
89-210 | |
HGF expression at the RNA level in the total three matched group | ||||
TxN0-2M1 | 30 | 232 | 78-337 | One way ANOVA p=0.014 TxN1-2M1vs TxN1-2M0 p=0.048 TxN1-2M1vs TxN0M0 p=0.009 TxN1-2M0vsTxN0M0 p=0.452 |
TxN1-2M1 | 21 | 163 | 90-266 | |
TxN0M0 | 30 | 138 | 67-210 | |
HGF expression at the RNA level in primary tumors and matched liver metastasis(TxN0M1) | ||||
Primary | 9 | 138 relative copies |
78-216 | paired t test p=0.758 3 cases showed similar at the RNA level in five cases with concordance at the protein level and one case showed similar in the four cases with disconcordance |
Liver | 9 | 146 relative copies |
96-232 | |
HGF expression at the RNA level in primary tumors and matched liver metastasis(TxN1-2M1) | ||||
Primary | 21 | 245 relative copies |
134-337 | paired t test p=0.617 17 cases showed similar at the RNA in 20 cases with concordance at the protein level and 1 case showed similar at the RNA level but different at the protein level |
Liver | 21 | 269 relative copies |
122-385 | |
HGF expression at the RNA level in primary tumors and matched liver metastasis(TxN0-2M1) | ||||
Primary | 30 | 232 | 78-337 | paired t test p=0.605 22 cases showed similar Concordance rate:73.3% |
Liver | 30 | 257 | 96-385 |
CI: confidence interval.