Table 6.
MET | Mean copy numbers | 95% CI | Statistical method and P value | ||
---|---|---|---|---|---|
MET expression at the RNA level in one subgroup of TxN0M1 and TxN0M0 | |||||
TxN0M1 | 9 | 1400 relative copies |
990-2012 | independent t test | |
TxN0M0 | 9 | 1298 relative copies |
787-1910 | p= 0.605 | |
MET expression at the RNA level in the other subgroup of TxN1-2M1, TxN1-2M0 and TxN0M0 | |||||
TxN1-2M1 | 21 | 1685 relative copies |
1340-2276 | One way ANOVA, P=0.031 TxN1-2M1vsTxN1-2M0,P=0.863 TxN1-2M1vsTxN0M0 P=0.018 TxN1-2M0vsTxN0M0 P=0.047 |
|
TxN1-2M0 | 21 | 1534 relative copies |
1100-2060 | ||
TxN0M0 | 21 | 1310 relative copies |
830-1914 | ||
MET expression at the RNA level in the total matched group | |||||
TxN0-2M1 | 30 | 1602 | 990-2276 | One way ANOVA, P=0.047 TxN1-2M1vsTxN1-2M0,P=0.932 TxN1-2M1vsTxN0M0 P=0.038 TxN1-2M0vsTxN0M0 P=0.046 |
|
TxN1-2M0 | 21 | 1534 relative copies |
1100-2060 | ||
TxN0M0 | 30 | 1301 | 787-1914 | ||
MET expression at the RNA level in primary tumors and matched liver metastasis(TxN0M1) | |||||
Primary | 9 | 1400 relative copies |
990-2012 | paired t test p=0.853 6 cases had similar relate copies. 5 cases in seven cases with concordance and 1 cases in 2 cases with disconcordance at the protein level |
|
Liver | 9 | 1498 relative copies |
869-2056 | ||
MET expression at the RNA level in primary tumors and matched liver metastasis(TxN1-2M1) | |||||
Primary | 21 | 1685 relative copies |
1340-2276 | paired t test p=0.853 17 cases showed similar at the RNA level. 14 cases in 17 cases with concordance and 3 cases in 4 cases with disconcordance at the protein level |
|
Liver | 21 | 1829 relative copies |
1227-2592 | ||
MET expression at the RNA level in primary tumors and matched liver metastasis(TxN0-2M1) | |||||
primary | 30 | 1602 relative copies |
paired t test p=0.709 22 cases showed similar at the RNA level Concordance rate:76.7% |
||
Liver | 30 | 1735 relative copies |
CI: confidence interval.