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Patients with viral breakthrough.
| ETV | LAM | |||
|---|---|---|---|---|
| Adherence rate | ≥90% | <90% | ≥90% | <90% |
| Resistance mutation (+) | 1 | 1 | 31 | 1 |
| L180M | 1 | 1 | N.D. | N.D. |
| T184A | 1 | 0 | N.D. | N.D. |
| S202G | 0 | 1 | N.D. | N.D. |
| M204V | 1 | 1 | 9 | 1 |
| M204I | 0 | 0 | 17 | 0 |
| M204V/I | 0 | 0 | 5 | 0 |
| M250V | 0 | 0 | N.D. | N.D. |
| Resistance mutation (-) | 1 | 1 | 0 | 2 |
ETV, entecavir; LAM, lamivudine; N.D., not determined. Numbers of amino acid positions were according to Refs. 2 and 10.
