Incidence of cardiovascular events according to the cross-classification of subjects by conventional and daytime ambulatory blood pressure in normotensives and in persons with solated systolic hypertension (ISH) presenting with white-coat hypertension, masked hypertension, and sustained hypertension. The analyses included all of the cardiovascular events according to the broad definition. Incidence was standardized to the sex distribution (45% men) and mean age (48.8 years) in the whole study population. In the analysis including untreated subjects only (left), the incidence of cardiovascular events was significantly higher in sustained (P=0.0005) and masked hypertension (P<0.0001) as compared with normotension, whereas the risk in white-coat hypertension was similar to that in normotension (P=0.38). Similarly, in treated subjects with ISH (right), the incidence of cardiovascular events was significantly higher in sustained (P<0.0001) and masked hypertension (P=0.0013) as compared with treated normotension, whereas the risk in treated white-coat hypertension was similar to that in treated normotension (P=0.92). In both treated and untreated patients with ISH, the risk was similar in sustained and masked hypertension (P>0.33).