Table 1.

Baseline parameters (mean±SD) in normal, sham-treated pigs with unilateral renal artery stenosis (RAS), and RAS pigs that improved or deteriorated stenotic kidney glomerular filtration rate (STK-GFR) after revascularization.

	Normal	Sham RAS	Improved STK-GFR	Deteriorated STK-GFR
Body weight (Kg)	46.4±3.6	49.1±4.0	43.7±5.4	47.4±3.0
Decrease in lumen diameter (%)	0	69.7±14.7^*	73.4±13.4^*	68.1±5.0^*
Area of stenosis (mm²)	0	89.8±10.2^*	90.8±15.0^*	89.9±11.1^*
Length of stenosis (mm)	0	6.4 ±1.8^*	6.6±2.0^*	6.5±1.8^*
Systolic blood pressure (mmHg)	113.0±8.2	144.6±24.2^*	146.5±20.2^*	156.2±4.5^*
Diastolic blood pressure (mmHg)	85.3±6.9	116.0±24.1^*	104.9±24.6^*	118.4±20.8^*
Mean Arterial Pressure (mmHg)	94.6±6.8	125.5±23.9^*	118.7±22.4^*	124.4±19.5^*
Serum creatinine (mg/dl)	1.2±0.1	1.8±0.3^*	1.8±0.2^*	1.9±0.4^*
Urinary albumin (µg/ml)	13.9±8.9	25.3±14.8	23.4±27.8	23.7±12.2
PRA IVC (ng/ml/hr)	0.26±0.09	0.22±0.21	0.33±0.49	0.25±0.20
PRA STK (ng/ml/hr)		0.27±0.10	0.24±0.11	0.22±0.17
PRA CLK (ng/ml/hr)		0.20±0.08	0.27±0.32	0.13±0.18

SD: standard deviation; PRA: plasma renin activity; IVC: inferior vena cava; STK: stenotic kidney; CLK: contralateral kidney.

p<0.05 vs. Normal,

p<0.05 vs. Sham RAS,

^†

p<0.05 vs. Improved STK-GFR (none observed for # and † comparisons).