Table 3.
MetS cluster z-score, HOMA-IR, glucose, insulin, triglycerides, HDL-C, and SBP according to BMI percentile and AN status.
| Variable | BMI < 85th percentile
|
BMI 85th – 94.9th percentile (overweight)
|
BMI ≥ 95th percentile (obese)
|
p-Value | ||
|---|---|---|---|---|---|---|
| − AN (n = 57) | −AN (n = 6) | + AN (n = 6) | −AN (n = 7) | + AN (n = 14) | ||
| MetS cluster z-score | − 0.31 (− 0.45 to − 0.16) | 0.02 (− 0.45 to 0.49) | 0.50 (− 0.21 to 1.21) b | 0.13 (− 0.34 to 0.60) | 0.97 (0.49 – 1.45) a | < 0.001 |
| HOMA-IR | 1.2 (1.0 – 1.5) | 1.5 (0.7 – 3.1) | 1.8 (1.1 – 3.2) | 1.6 (0.8 – 3.2) | 3.9 (2.8 – 5.4) c | < 0.001 |
| Insulin, pmol/L | 38.89 (32.64 – 45.84) | 47.92 (24.31 – 95.84) | 61.81 (36.81 – 103.48) | 53.48 (28.47 – 102.09) | 118.86 (88.9 – 159.04) c | < 0.001 |
| Glucose, mmol/L | 4.94 (4.83 – 5.05) | 4.88 (4.55 – 5.27) | 4.66 (4.44 – 4.88) | 4.77 (4.55 – 5.0) | 5.11 (4.88 – 5.33) | 0.10 |
| Triglyceride, mmol/L | 0.82 (0.76 – 0.90) | 0.97 (0.71 – 1.31) | 1.07 (0.69 – 1.67) | 1.12 (0.96 – 1.32) | 1.27 (0.99 – 1.62) | < 0.001 |
| HDL-C, mmol/L | 1.27 (1.19 – 1.35) | 1.17 (1.04 – 1.27) | 0.98 (0.83 – 1.11) | 1.01 (0.91 – 1.11) | 0.91 (0.80 – 1.04) b | < 0.001 |
| SBP, mm Hg | 99 (97 – 101) | 103 (91 – 115) | 108 (101 – 116) | 98 (87 – 109) d | 107 (103 – 111) | 0.001 |
Total cholesterol and LDL cholesterol were not measured as they are not components of the MetS. Values are mean (95 % CI) for MetS cluster z-score, HDL-C, and SBP; values are geometric mean (95 % CI) for HOMA-IR, insulin, and triglycerides.
a
Significantly different from BMI < 85th percentile, overweight BMI with no AN, and obese BMI with no AN.
b
Significantly different from BMI < 85th percentile.
c
Significantly different from all other groups.
d
Significantly different from overweight BMI with AN.