Table 1. Strategies to Generate Antigen-Loaded Dendritic Cells for Cancer Immunotherapy.

Strategy 1

Ex vivo antigen loading, activation, and re-infusion of autologous dendritic cells for cancer immunotherapy.

Strategy 2

Delivery of antigen and costimulatory molecules to resident dendritic cells by targeting antigen delivery to mannose receptors, and delivering costimulatory signals.

Strategy 3

Recombinant viral vectors that express antigen and costimulatory molecules to resident dendritic cells and infect them directly or express antigen that is processed and presented by dendritic cells.