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. Author manuscript; available in PMC: 2013 Mar 25.
Published in final edited form as: Hypertension. 2012 Nov 19;61(1):18–26. doi: 10.1161/HYPERTENSIONAHA.112.197376

Table 3. Predictive Value of the Cox Regression Models.

Cardiovascular Mortality
 Cardiovascular Events
 Stroke
Models Likelihood Ratio P Value R2 (%) Likelihood Ratio P Value R2 (%) Likelihood Ratio P Value R2 (%)
Basic model 445.0 … 8.03 809.7 … 14.1 353.6 … 6.40
24-h systolic pressure added to
basic model		 19.3 <0.0001 0.35 62.7 <0.0001 1.17 53.3 <0.0001 1.00
eGFR added to basic model 6.8 0.012 0.12 4.4 0.035 0.08 7.0 0.009 0.13
eGFR added to basic model also
including 24-h systolic pressure		 6.7 0.010 0.13 4.6 0.033 0.09 7.2 0.007 0.14

The basic model included cohort, sex, age, body mass index, smoking and drinking, serum cholesterol, history of cardiovascular disease, diabetes mellitus, and treatment with antihypertensive drugs. P values are for the improvement of the fit across nested models. Values are likelihood ratios and associated P values and generalized R2 statistics for adding 24-h systolic blood pressure or eGFR to the reference model. eGFR indicates estimated glomerular filtration rate.