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. Author manuscript; available in PMC: 2014 Mar 15.
Published in final edited form as: Cancer Res. 2013 Jan 9;73(6):1892–1899. doi: 10.1158/0008-5472.CAN-12-2609

Figure 1.

Figure 1

The experimental MRI-guided FUS setup. The anesthetized animal was positioned supine over an MRI RF surface coil and coupled to the piezo-ceramic focused transducer through a bath of de-gassed water. The transducer was repositioned with the aid of a computer-controlled three-axis positioning system, allowing the ultrasound focus to reach any point within the brain. The entire setup fits in the bore of the 1.5T MR scanner, allowing for coordinate co-registration, targeting and confirmation of BBBD.