Table II.
Demographic and clinical characteristics of patients presenting with spontaneous preterm labor (PTL) and intact membranes.
|
|
||||||
|---|---|---|---|---|---|---|
| PTL without IAI, Term delivery (n=62) |
pa | PTL without IAI, Preterm delivery (n=30) |
pb | PTL with IAI, Preterm delivery (n=67) |
pc | |
| Maternal age (years)† | 22 (19-26.2) | NS | 23 (18.7-27.5) | NS | 22 (19-27) | NS |
| Ethnic origin | ||||||
| African-American | 50 (31) | 0.003 | 83.3 (25) | 0.03 | 62.7 (42) | NS |
| Caucasian | 4.8(3) | 6.7 (2) | 13.4 (9) | |||
| Hispanic | 43.5 (27) | 10 (3) | 22.4(15) | |||
| Asian and other | 1.6(1) | 0 (0) | 1.5(1) | |||
| Smokers (%) | 29.1 (16/55) | NS | 23.3 (7) | NS | 37.8 (17/45) | NS |
| Pre-pregnancy BMI (kg/m2)† | 21.4 (19.5-25) | NS | 22.5 (21.5-25.1) | NS | 24.5 (21.2-30.2) | 0.01 |
| GA at blood sample collection (weeks)† | 31.5 (29.4-33.1) | NS | 31 (26-32.5) | NS | 27.4 (24.9-32.4) | <0.001 |
| GA at delivery (weeks)†† | 38.7(38-39.5) | <0.001 | 34.5 (31.1-35.3) | <0.001 | 28.1 (25.2-32.9) | <0.001 |
| Neonatal birthweight (grams)‡ | 3143 (2870-3410) | <0.001 | 2100 (1569-2470) | 0.001 | 1100 (709-1960) | <0.001 |
| Sample storage time (years)† | 7.6 (6.6-8.7) | NS | 7.3 (7.0-8.1) | NS | 7.5 (6.8-8.6) | NS |
Values expressed as median (interquartile range) or percentage (number) PTL: preterm labor; IAI: intra-amniotic infection/inflammation; BMI: body mass index; GA: gestational age; NS: not significant.
a
comparison between PTL without IAI, term delivery and PTL without IAI, preterm delivery
b
comparison between PTL without IAI, preterm delivery and PTL with IAI, preterm delivery
c
comparison between PTL without IAI, preterm delivery and PTL with IAI, preterm delivery.
†
Kruskal-Wallis, p=NS,
††
Kruskal-Wallis, p<0.05,
‡
Kruskal-Wallis, p=0.001