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. 2012 Jul 31;21(22):4817–4826. doi: 10.1093/hmg/dds311

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© The Author 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Increased motor activity after L-DOPA injection. Animals were analyzed by an open field test after a control saline injection to obtain baseline activity. They were tested a second time after an L-DOPA injection. Quantification of open field data for total distance traveled (A) and rearing frequency (B). For each animal, the activity after L-DOPA treatment was normalized to the activity after the saline injection. The Student's t-test was used to obtain P-values (*P < 0.05; **P < 0.001; n = 10–15 per genotype), and error bars represent the propagated error.