Table 4.

RIFLE Criteria (Acute Dialysis Quality Initiative)

Stage	Serum Creatinine Criteria	GFR Criteria	Urine Output Criteria
R = Risk for renal dysfunction	Increase in serum creatinine ≥ 1.5× baseline	Decrease in GFR ≥ 25%	< 0.5 mL/kg/hr for 6 h
I = Injury to the kidney	Increase in serum creatinine ≥ 2.0 × baseline	Decrease in GFR ≥ 50%	< 0.5 mL/kg/hr for 12h
F = Failure of kidney function	Increase in serum creatinine ≥ 3.0× baseline OR serum creatinine ≥ 4.0 mg/dL in the setting of an acute rise ≥ 0.5 mg/dL	Decrease in GFR ≥ 75%	< 0.3 mL/kg/hr for 24 hr or anuria for 12 hr
L = Loss of kidney function	Persistent failure > 4 weeks
E = End-stage renal disease (ESRD)	Persistent failure > 3 months

Note: GFR – glomerular filtration rate, mg/dl – milligrams/deciliter, and the urine output criteria are the same for both RIFLE and AKIN.