TABLE 4.
n | Weight (g)
|
Total cholesterol (mg/dl)
|
|||||
---|---|---|---|---|---|---|---|
Mean ± SEM (range)
|
Mean ± SEM (range)
|
||||||
Week 0 | Week 14 | p | Week 0 | Week 14 | p | ||
Group 1 (male guinea pigs fed a normal diet) | 7 | 175.0 ± 11.1 (135–217) | 745.6 ± 18.0 (693 –796) | < 0.01* | 53.7 ± 5.56 (33–77) | 58.3 ± 6.87 (40–97) | 0.63 |
Group 2 (male guinea pigs fed a high-fat diet) | 9 | 167.0 ± 5.2 (149–188) | 602.4 ± 18.4 (497 –669) | < 0.01* | 61.4 ± 3.24 (50–79) | 719.9 ± 90.39 (345 –1,042) | < 0.01* |
Group 3 (female guinea pigs fed a high-fat diet) | 8 | 141.4 ± 8.5 (116–178) | 567.3 ± 37.2 (347 –693) | < 0.01* | 70.0 ± 10.38 (50–140) | 442.1 ± 62.98 (271 –829) | < 0.01* |
SEM indicates standard error of the mean.
p values were determined by using a paired Student’s t test. An asterisk indicates statistical significance.