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Biodistribution of free anti-TfR-R17 vs. nanocarriers coated with anti-TfR-R17. Localization ratio (LR) and specificity index (SI) of brain, lungs, and liver are shown in (A) and (B), respectively. Data are mean ± S.E.M. (n ≥ 3 mice). * p < 0.05; ** p < 0.01, *** p < 0.001, comparing anti-TfR-R17 to anti-TfR-R17 NCs, by Student’s t-test. NCs = nanocarriers.
