Table 3.
Comparison of trials

For this table, poorly differentiated or undifferentiated cases were added to the adenocarcinoma totals.
aITT calculation of pCR calculated as pCR/(all patients who received therapy). Of note, some studies did not require patients to proceed to surgery (Ilson et al. [4], Safran et al. [17]).
Abbreviations: 5-FU, 5-fluorouracil; ARDS, acute respiratory distress syndrome; ITT, intention to treat; LV, leucovorin; NR, not reported; pCR, pathologic complete response; PE, pulmonary embolism; SCC, squamous cell carcinoma; XRT, radiation therapy.