Table 1.
RMP, mV | APA, mV | APD50, ms | APD90, ms | |
---|---|---|---|---|
EGFP+ Mlc2vCre/+ | −66.6 ± 0.7 | 123.8 ± 4.5 | 12.9 ± 0.7 | 41.0 ± 2.8 |
EGFP+ Mlc2vCre/+; NICD | −62.6 ± 1.8 | 115.0 ± 2.1 | 27.2 ± 4.1* | 87.5 ± 12.3* |
EGFP− Mlc2vCre/+ | 61.9 ± 3.3 | 110.5 ± 4.4 | 14.6 ± 0.8 | 40.8 ± 0.6 |
EGFP− Mlc2vCre/+; NICD | 67.6 ± 1.6 | 116.2 ± 6.5 | 16.8 ± 2.1 | 50.4 ± 9.9 |
Data are expressed as mean ± SEM.
p<0.05.
n =9 EGFP+ Mlc2vCre/+, n=11 EGFP+ Mlc2vCre/+; NICD, n=4 EGFP− Mlc2vCre/+, n=5 EGFP− Mlc2vCre/+; NICD. RMP = resting membrane potential; APA = action potential
amplitude; APD50 = action potential at 50% repolarization; APD90 = action potential at 90% repolarization.