Table 3. Multivariate odds ratio (ORs) and 95% confidence intervals (CIs) of eGFR decline according to tertiles or categories of anthropometric measures.
| Measures | Category/Tertile | ≥3 decline | 20% decline | ≥3 or 20% decline | 60> eGFR | ||||
| No. of case | OR (95% CI) | No. of case | OR (95% CI) | No. of case | OR (95% CI) | No. of case | OR (95% CI) | ||
| BMIa (kg/m2) | <23 | 20 | 1.00 | 21 | 1.00 | 22 | 1.00 | 12 | 1.00 |
| 23−<25 | 20 | 1.13(0.53–2.42) | 23 | 1.24(0.61–2.54) | 23 | 1.16(0.57–2.37) | 12 | 1.08(0.43–2.67) | |
| 25−<30 | 30 | 1.05(0.51–2.17) | 31 | 1.01(0.51–2.01) | 33 | 1.00(0.51–1.98) | 22 | 1.24(0.54–2.84) | |
| ≥30 | 10 | 2.15(0.80–5.77) | 10 | 2.14(0.82–5.58) | 11 | 2.21(0.86–5.67) | 6 | 2.12(0.67–6.76) | |
| P-trend | 0.3 | 0.3 | 0.3 | 0.2 | |||||
| BMIb (kg/m2) | <23 | 20 | 1.00 | 21 | 1.00 | 22 | 1.00 | 12 | 1.00 |
| 23−<25 | 20 | 0.85(0.38–1.93) | 23 | 0.90(0.42–1.94) | 23 | 0.88(0.41–1.89) | 12 | 0.75(0.29–1.97) | |
| 25−<30 | 30 | 0.62(0.24–1.55) | 31 | 0.54(0.23–1.31) | 33 | 0.59(0.25–1.40) | 22 | 0.59(0.21–1.69) | |
| ≥30 | 10 | 0.96(0.26–3.57) | 10 | 0.85(0.24–2.98) | 11 | 0.99(0.29–3.43) | 6 | 0.70(0.16–3.16) | |
| P-trend | 0.7 | 0.5 | 0.7 | 0.5 | |||||
| WCa (cm) | M: < = 90, F: < = 85 | 23 | 1.00 | 27 | 1.00 | 28 | 1.00 | 16 | 1.00 |
| M: >90, F: >85 | 18 | 2.63(1.22–5.65) | 17 | 2.00(0.96–4.16) | 18 | 2.00(0.97–4.13) | 11 | 2.80(1.14–6.92) | |
| M: >95, F: >90 | 21 | 2.49(1.15–5.38) | 24 | 2.38(1.17–4.83) | 25 | 2.35(1.16–4.74) | 17 | 2.84(1.22–6.61) | |
| P-trend | 0.01 | 0.01 | 0.01 | 0.01 | |||||
| WCc (cm) | M: < = 90, F: < = 85 | 23 | 1.00 | 27 | 1.00 | 28 | 1.00 | 16 | 1.00 |
| M: >90, F: >85 | 18 | 2.98(1.26–7.02) | 17 | 2.11(0.94–4.74) | 18 | 2.24(1.00–5.01) | 11 | 2.88(1.06–7.79) | |
| M: >95, F: >90 | 21 | 3.17(1.10–9.13) | 24 | 2.65(1.00–6.99) | 25 | 2.93(1.12–7.69) | 17 | 2.98(0.94–9.48) | |
| P-trend | 0.02 | 0.04 | 0.02 | 0.05 | |||||
| Weightd (cm) | T1 | 31 | 1.00 | 30 | 1.00 | 32 | 1.00 | 16 | 1.00 |
| T2 | 25 | 0.96(0.48–1.92) | 28 | 1.13(0.58–2.20) | 29 | 1.05(0.54–2.03) | 17 | 1.36(0.58–3.21) | |
| T3 | 26 | 1.30(0.58–2.95) | 29 | 1.40(0.64–3.10) | 30 | 1.28(0.59–2.80) | 21 | 2.09(0.76–5.75) | |
| P-trend | 0.6 | 0.4 | 0.5 | 0.2 | |||||
| Heighte (cm) | T1 | 30 | 1.00 | 29 | 1.00 | 31 | 1.00 | 16 | 1.00 |
| T2 | 25 | 1.13(0.54–2.35) | 27 | 1.21(0.59–2.48) | 28 | 1.22(0.60–2.48) | 14 | 1.53(0.59–3.93) | |
| T3 | 25 | 1.84(0.58–5.84) | 29 | 1.62(0.54–4.85) | 30 | 1.82(0.61–5.43) | 22 | 3.87(0.91–16.5) | |
| P-trend | 0.3 | 0.4 | 0.3 | 0.06 | |||||
| Hip circumferencea (cm) | T1 | 13 | 1.00 | 15 | 1.00 | 16 | 1.00 | 11 | 1.00 |
| T2 | 25 | 2.29(1.04–5.03) | 28 | 2.24(1.08–4.67) | 29 | 2.10(1.02–4.31) | 19 | 2.16(0.90–5.14) | |
| T3 | 24 | 1.95(0.87–4.38) | 25 | 1.88(0.88–3.99) | 26 | 1.70(0.81–3.57) | 14 | 1.56(0.63–3.89) | |
| P-trend | 0.1 | 0.1 | 0.2 | 0.4 | |||||
| WHRa | T1 | 21 | 1.00 | 21 | 1.00 | 22 | 1.00 | 7 | 1.00 |
| T2 | 13 | 0.52(0.23–1.19) | 13 | 0.49(0.22–1.08) | 15 | 0.56(0.26–1.20) | 9 | 1.15(0.40–3.35) | |
| T3 | 28 | 1.64(0.80–3.35) | 34 | 1.76(0.90–3.43) | 34 | 1.74(0.89–3.39) | 28 | 3.94(1.55–9.97) | |
| P-trend | 0.1 | 0.04 | 0.05 | 0.001 | |||||
| WHtRa | T1 | 16 | 1.00 | 20 | 1.00 | 21 | 1.00 | 10 | 1.00 |
| T2 | 14 | 0.86(0.38–1.98) | 14 | 0.62(0.29–1.35) | 14 | 0.58(0.27–1.27) | 9 | 0.85(0.32–2.29) | |
| T3 | 32 | 2.25(1.02–4.97) | 34 | 1.76(0.85–3.64) | 36 | 1.79(0.88–3.67) | 25 | 3.04(1.22–7.61) | |
| P-trend | 0.03 | 0.08 | 0.07 | 0.01 | |||||
| Body fat massa (kg) | T1 | 22 | 1.00 | 24 | 1.00 | 25 | 1.00 | 13 | 1.00 |
| T2 | 17 | 0.69(0.33–1.48) | 19 | 0.75(0.37–1.53) | 19 | 0.70(0.34–1.42) | 15 | 1.51(0.65–3.55) | |
| T3 | 28 | 1.20(0.57–2.54) | 30 | 1.27(0.63–2.58) | 32 | 1.29(0.64–2.59) | 20 | 2.07(0.87–4.95) | |
| P-trend | 0.5 | 0.4 | 0.4 | 0.1 | |||||
| Body fat percenta (%) | T1 | 18 | 1.00 | 20 | 1.00 | 21 | 1.00 | 13 | 1.00 |
| T2 | 20 | 1.08(0.49–2.39) | 23 | 1.22(0.58–2.56) | 23 | 1.15(0.55–2.39) | 18 | 1.31(0.56–3.07) | |
| T3 | 29 | 1.25(0.51–3.09) | 30 | 1.47(0.62–3.50) | 32 | 1.46(0.62–3.42) | 17 | 1.43(0.50–4.13) | |
| P-trend | 0.6 | 0.4 | 0.4 | 0.5 | |||||
Abbreviations: OR, odds ratio; CI, confidence interval; M, male; F, female; eGFR, estimated glomerular filtration rate; BMI, body mass index; WC, waist circumference.
a
Adjusted for age (continuous), sex, baseline eGFR (continuous), pack-years of smoking (continuous), duration of education (none, 1 to <6 years, ≥6 years), total energy intake (continuous), and history of hypertension or diabetes (yes, no).
b
Adjusted for variables above and WC (continuous).
c
Adjusted for variables above and BMI (continuous).
d
Adjusted for variables above and height (continuous).
e
Adjusted for variables above and weight (continuous).