Table 1. Genes regulated by IL-33 in BMDM (mRNA expression by real-time qPCR).
Genes | VEH | IL-33 (20 ng/ml) 72 hours | |
Up-regulated | IL13 | 1±0.1 | 43238±4864 |
IL4 | 1±0.1 | 4.8±0.5 | |
IL5 | 1±0.2 | 1552±396 | |
ARG1 | 1±0.1 | 416±62 | |
CD206 | 1±0.1 | 2.2±0.2 | |
YM-1 | 1±0.1 | 15.5±7.7 | |
NOS2 | 1±0.2 | 7.6±0.2 | |
IFNγ | 1±0.4 | 5.7±1.2 | |
IL6 | 1±0 | 15.6±1 | |
GATA3 | 1±0.1 | 5.7±1 | |
Junb | 1±0.1 | 2.3±0.4 (24 hour) | |
Maf | 1±0.5 | 3.4±0.7 | |
CCL2 | 1±0.1 | 9.8±0.6 | |
CCL17 | 1±0.1 | 5±1 | |
CCL24 | 1±0 | 9.6±1.7 | |
CD11b | 1±0.1 | 1.5±0.1 | |
CD86 | 1±0 | 1.5±0 | |
IL1RL1 | 1±0 | 2.2±0.4 | |
Down-regulated | DEC2 | 1±0.1 | 0.5±0 |
IL17RA | 1±0 | 0.5±0 | |
Tbx21 | 1±0.1 | 0.3±0.1 | |
TGFβ3 | 1±0 | 0.4±0 | |
IL12p40 | 1±0.4 | 0.1±0 |
BMDM: bone marrow-derived macrophages.