TABLE 2.
Baseline characteristics of 1576 US male physicians across quintiles of plasma phospholipid TFAs1
| Plasma trans 16:1 |
Plasma trans 18:1 |
Plasma trans 18:2 |
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| Characteristics | Q1 (low) | Q3 | Q5 (high) | P-trend | Q1 (low) | Q3 | Q5 (high) | P-trend | Q1 (low) | Q3 | Q5 (high) | P-trend |
| n | 295 | 326 | 292 | 332 | 312 | 298 | 323 | 314 | 282 | |||
| Plasma TFAs (% of total fatty acids)2 | 0.05 (0.02, 0.06) | 0.08 (0.08, 0.09) | 0.12 (0.11, 0.26) | 0.98 (0.60, 1.16) | 1.57 (1.44, 1.70) | 2.37 (2.08, 4.10) | 0.24 (0.15, 0.28) | 0.36 (0.33, 0.39) | 0.51 (0.45, 2.71) | |||
| BMI (kg/m2) | 24.9 ± 2.53 | 25.1 ± 2.9 | 25.0 ± 2.6 | 0.98 | 25.5 ± 3.1 | 25.2 ± 2.9 | 24.8 ± 2.5 | <0.01 | 25.4 ± 2.9 | 25.0 ± 2.8 | 25.0 ± 2.8 | 0.06 |
| Age (y) | 58.5 ± 7.6 | 59.5 ± 8.3 | 58.0 ± 7.7 | 0.46 | 58.5 ± 7.7 | 58.8 ± 8.1 | 59.1 ± 8.1 | 0.56 | 58.9 ± 7.8 | 58.2 ± 8.0 | 58.3 ± 7.9 | 0.05 |
| Prevalent atrial fibrillation (%) | 3.7 | 3.4 | 3.8 | 0.78 | 5.1 | 2.9 | 3.7 | 0.58 | 2.5 | 3.8 | 2.1 | 0.73 |
| History of CABG (%) | 1.7 | 1.5 | 1.4 | 0.78 | 1.2 | 0.3 | 1.0 | 0.70 | 2.8 | 2.9 | 0.7 | 0.06 |
| History of CAD (%) | 3.1 | 3.1 | 3.1 | 1.00 | 3.3 | 0.6 | 4.0 | 0.73 | 5.0 | 4.5 | 2.5 | 0.07 |
| Prevalent type 2 diabetes (%) | 4.4 | 6.4 | 5.5 | 0.34 | 8.1 | 4.2 | 4.0 | 0.05 | 6.2 | 6.1 | 5.0 | 0.49 |
| Hypertension (%) | 35.9 | 31.3 | 26.7 | <0.01 | 36.8 | 28.2 | 25.5 | <0.01 | 36.5 | 26.8 | 32.3 | 0.13 |
| High cholesterol (%) | 16.6 | 10.4 | 13.7 | 0.02 | 16.9 | 12.8 | 9.7 | <0.01 | 18.9 | 13.4 | 11.7 | 0.01 |
| Exercise (%) | 70.5 | 74.2 | 73.3 | 0.35 | 64.5 | 76.3 | 78.2 | <0.01 | 67.5 | 75.5 | 75.5 | 0.01 |
| Smoking status (%) | ||||||||||||
| Never | 36.6 | 46.6 | 52.1 | <0.01 | 34.3 | 46.2 | 56.4 | <0.01 | 41.2 | 46.5 | 48.9 | 0.02 |
| Past | 49.2 | 43.3 | 38.4 | <0.01 | 50.3 | 41.7 | 34.6 | <0.01 | 50.2 | 42.4 | 39.7 | 0.01 |
| Current | 13.9 | 10.1 | 9.3 | 0.08 | 15.1 | 12.2 | 9.1 | 0.03 | 8.4 | 11.2 | 11.0 | 0.55 |
| Alcohol (%) | ||||||||||||
| Rarely | 6.8 | 15.3 | 26.0 | <0.01 | 6.0 | 15.7 | 27.5 | <0.01 | 9.9 | 17.5 | 22.0 | <0.01 |
| Monthly | 6.8 | 9.5 | 12.3 | 0.01 | 7.5 | 8.3 | 11.7 | 0.03 | 10.2 | 8.9 | 9.9 | 0.95 |
| Weekly | 40.3 | 47.9 | 43.5 | 0.26 | 41.3 | 48.1 | 46.0 | 0.27 | 48.3 | 43.3 | 43.3 | 0.21 |
| Daily | 46.1 | 26.7 | 17.8 | <0.01 | 44.9 | 26.9 | 14.1 | <0.01 | 31.0 | 29.6 | 24.5 | 0.07 |
1
Except for BMI and age, data for other characteristics were not provided by all individuals; quintiles were created by using TFA distribution in the control series. CABG, coronary artery bypass grafting; CAD, coronary artery disease; Q, quintile; TFA, trans fatty acid.
2
Values are medians; ranges in parentheses.
3
Mean ± SD (all such values).