TABLE 5.
HRs (95% CIs) of heart failure according to quintiles of dietary TFAs (from FFQs)1
| Quintile of TFA ( g/d ) | No. of cases/person-years | Model 1 | Model 2 | Model 3 |
| Q1 (ref): 0.87 (0.025, 1.12) | 144/40,378 | 1.00 | 1.00 | 1.00 |
| Q2: 1.33 (1.13, 1.50) | 165/39,830 | 1.14 (0.91, 1.42) | 1.10 (0.88, 1.38) | 1.13 (0.90, 1.42) |
| Q3: 1.69 (1.51, 1.84) | 156/39,469 | 1.04 (0.83, 1.30) | 0.99 (0.79, 1.25) | 1.03 (0.82, 1.30) |
| Q4: 2.04 (1.85, 2.26) | 184/38,610 | 1.26 (1.01, 1.57) | 1.12 (0.90, 1.40) | 1.18 (0.94, 1.48) |
| Q5: 2.60 (2.27, 5.32) | 182/37,857 | 1.21 (0.97, 1.51) | 1.03 (0.82, 1.29) | 1.11 (0.88, 1.39) |
| P-trend | — | 0.05 | 0.80 | 0.39 |
| Modeled as continuous variable2 | — | 1.07 (1.00, 1.15) | 1.01 (0.94, 1.08) | 1.03 (0.96, 1.10) |
1
Quintile values are medians; ranges in parentheses. Number of subjects per model: model 1, 19,768; model 2, 19,301; and model 3, 19,214. Model 1 adjusted for age; model 2 adjusted as for model 1 plus additionally adjusted for diabetes, smoking, alcohol, exercise, BMI, and atrial fibrillation; and model 3 adjusted as for model 2 plus additionally adjusted for coronary artery disease and hypertension. Analyses were performed by using proportional hazards regression. FFQ, food-frequency questionnaire; Q, quintile; ref, reference; TFA, trans fatty acid.
2
ORs per SD increase in dietary TFAs (0.69 g/d).