Table 3.
Imputed (I) and subsequently genotyped chromosome 8 SNPs surrounding TSPYL5 (all with P < 5E-08). O, observed during GWAS genotyping
| SNP | Chr | bp Positiona | Effectb | Lower 95% CI | Upper 95% CI | P Value | MAF | Imputed (I) or Observed (O) |
|---|---|---|---|---|---|---|---|---|
| rs2451114 | 8 | 98273762 | 1.64441 | 1.402311 | 1.928305 | 1.50E-09 | 0.100361 | I |
| rs2451113 | 8 | 98273448 | 1.63402 | 1.389243 | 1.921925 | 4.62E-09 | 0.093637 | I |
| rs2439702 | 8 | 98272647 | 1.631933 | 1.385699 | 1.921922 | 6.60E-09 | 0.093863 | I |
| rs2053480 | 8 | 98278951 | 1.627991 | 1.383235 | 1.916056 | 6.84E-09 | 0.093149 | I |
| rs2567773 | 8 | 98279182 | 1.627991 | 1.383235 | 1.916056 | 6.84E-09 | 0.092659 | I |
| rs2853312 | 8 | 98281319 | 1.619799 | 1.377337 | 1.904943 | 8.27E-09 | 0.094952 | I |
| rs2635162 | 8 | 98283629 | 1.621225 | 1.374058 | 1.912853 | 1.50E-08 | 0.098439 | I |
| rs2583506 | 8 | 98281847 | 1.614156 | 1.369888 | 1.90198 | 1.55E-08 | 0.101205 | I |
| rs1348184 | 8 | 98276912 | 1.615936 | 1.37075 | 1.90498 | 1.58E-08 | 0.098558 | I |
| rs2053481 | 8 | 98278923 | 1.615936 | 1.37075 | 1.90498 | 1.58E-08 | 0.098439 | I |
| rs2439700 | 8 | 98277168 | 1.615936 | 1.37075 | 1.90498 | 1.58E-08 | 0.098193 | I |
| rs2853318 | 8 | 98283509 | 1.611976 | 1.367697 | 1.899885 | 1.78E-08 | 0.097839 | I |
| rs2853320 | 8 | 98283523 | 1.611976 | 1.367697 | 1.899885 | 1.78E-08 | 0.097839 | I |
| rs2583504 | 8 | 98283404 | 1.612618 | 1.367138 | 1.902177 | 2.03E-08 | 0.098676 | I |
| rs1431891 | 8 | 98282716 | 1.606092 | 1.362664 | 1.893006 | 2.29E-08 | 0.099159 | I |
| rs1835743 | 8 | 98282643 | 1.606092 | 1.362664 | 1.893006 | 2.29E-08 | 0.09904 | I |
| rs2635161 | 8 | 98282907 | 1.606092 | 1.362664 | 1.893006 | 2.29E-08 | 0.098676 | I |
| rs1864729 | 8 | 98282189 | 1.589376 | 1.350376 | 1.870676 | 3.49E-08 | 0.09807 | O |
a
Genome Build 37.
b
Multiplicative effect from quasi-likelihood model.