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. Author manuscript; available in PMC: 2013 Mar 26.
Published in final edited form as: Neuron. 2011 Jun 9;70(5):898–907. doi: 10.1016/j.neuron.2011.05.021

Figure 2.

Figure 2

Gene clusters found using NETBAG analysis of de novo CNV regions observed in autistic individuals. A) The highest scoring cluster obtained using the search procedure with up to one gene per each CNV region. B) The cluster obtained using the search with up to two genes per region. In the figure genes (nodes) with known functions in the brain and nervous systems are colored in orange (see Table S2 for functional information about the genes forming the cluster). Node sizes represent the importance of each gene to the overall cluster score. Edge widths are proportional to the prior likelihood that the two corresponding genes contribute to a shared genetic phenotype. For clarity, we show only edges corresponding to the two strongest connections for at least one node.