Table 2.
Systemic hemodynamic variables in response to fluid challenge
| Variable | All (n = 50) | Low MFI (n = 33) | High MFI (n = 17) | |||
|---|---|---|---|---|---|---|
| Baseline | FC | Baseline | FC | Baseline | FC | |
| MAP, mmHg | 66 (59–75) | 68 (61–79) | 66 (58–74) | 68 (59–79) | 64 (59–79) | 68 (66–85) |
| HR, beats/min | 91 (90–106) | 90 (86–100)† | 91 (88–109) | 90 (84–105)‡ | 94 (90–104) | 90 (89-100)‡ |
| CVP, mmHg | 9 (7–12) | 11 (9–14)† | 9 (8–13) | 11 (9–14)† | 8 (6–11) | 10 (6–13) |
| SVi, ml/m2 | 25 (19–32) | 29 (23–38)† | 22 (19–29) | 26 (23–31)† | 28 (21–29) | 31 (25–34)† |
| ΔSVi >10 %, n (%) | 34 (68) | 23 (70) | 11 (65) | |||
| S(c)vO2 | 69 (62–73) | 72 (65–78)† | 69 (62–73) | 72 (63-79)† | 67 (60–73) | 71 (66–79) |
| Lactate, mmol/l | 2.2 (1.6–4.2) | 2.2 (1.4–3.9) | 2.8 (1.7–4.2) | 2.7 (1.7–3.9) | 1.7 (1.4–4.7) | 1.5 (1.2–4.2) |
MAP mean arterial pressure, HR heart rate, CVP central venous pressure, SV i stroke volume index, S(c)vO 2 mixed/central venous oxygen saturation, low MFImicrovascular flow index <2.6, high MFI microvascular flow index ≥2.6, FC fluid challenge. All data presented as median (IQR)
† p ≤ 0.005, ‡ p < 0.05, difference in comparison with baseline