Table 3.
Microcirculatory variables in response to fluid challenge
| Variable | All (n = 50) | Low MFI (n = 33) | High MFI (n = 17) | |||
|---|---|---|---|---|---|---|
| Baseline | FC | Baseline | FC | Baseline | FC | |
| MFI s | 2.5 (2.3–2.8) | 2.7 (2.4–2.8)† | 2.3 (2.0–2.5) | 2.5 (2.1–2.8)† | 2.8 (2.8–2.9) | 2.8 (2.7–3) |
| MFI l | 3 (2.9–3) | 3 (3–3) | 3 (2.9–3) | 3 (3–3) | 3 (2.9–3) | 3 (3–3) |
| Het MFI | 0.3 (0.1–0.3) | 0.2 (0.1–0.3) | 0.3 (0.2–0.5) | 0.3 (0.1–0.4) | 0.2 (0.1–0.2) | 0.2 (0.1–0.3) |
| PPV s (%) | 90 (86–93) | 91 (89–95)† | 88 (84–91) | 91 (84–94)† | 94 (92–95) | 94 (91–96) |
| TVD s, mm/mm2 | 29 (27–34) | 31 (26–34) | 30 (27–34) | 31 (26–36) | 27 (25–32) | 28 (23–32) |
| PVD s, 1/mm | 14 (12–17) | 15 (13–18) | 14 (12–17) | 16 (13–18) | 15 (14–16) | 15 (12–17) |
MFI s microvascular flow index small vessels (<20 μm), MFI l microvascular flow index large vessels (≥20 μm), Het MFI coefficient of MFI s variation, PPV s percentage of perfused small vessels, TVD s total vessel density small vessels, PVD s perfused vessel density small vessels, low MFI microvascular flow index <2.6, high MFI microvascular flow index ≥2.6, FC fluid challenge. All data presented as median (IQR). † p ≤ 0.005 in comparison with baseline